Doreen Manuela Floss

9PUBLICATIONS
40CO-AUTHORS
Applied immunology (incl. antibody engineering, xenotransplantation and t-cell therapies)Chemical engineering designMolecular targetsBiomaterialsEvolution of developmental systems
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Publications (9)

|Oct 14, 2026
Selective inhibition of IL-6 trans-signalling reveals distinct mechanisms of human classic and trans-signalling receptor-complex formation.

|Jan 06, 2026
Receptor engineering constitutes feedback control and robustness of IL-23R signaling and highlights importance of intracellular cytokine receptor signaling motifs.

Leorina Kashtanjeva, Christin Ruhland, Franz Christian Horstmeier

|Nov 20, 2025
SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1.

Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel

|Sep 25, 2025
iBody-mediated tuning of synthetic cytokine receptor activation via rational nanobody interface engineering.

Richard Kunze, Fabian Navratil, Joana Beichert

|Jun 27, 2025
Functional analysis of CYP4B1 enzymes from apes and humans uncovers evolutionary hot spots for adaptations of the catalytical function.

Saskia Hüsken, Annika Röder, Johannes Ptok

|May 02, 2024
Unpaired cysteine insertions favor transmembrane dimerization and induce ligand-independent constitutive cytokine receptor signaling.

Lynn Affrica Felicitas Baumgärtner, Julia Ettich, Helene Balles

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Frequent Collaborators

5 joint publications

Jürgen Scheller

3 joint publications

Roland P Piekorz

2 joint publications

Constanze Wiek

2 joint publications

Mohammad R Ahmadian