David Lee Williams

11PUBLICATIONS
35CO-AUTHORS
Major global burdens of diseaseBiologically active moleculesCharacterisation of biological macromoleculesBiomolecular modelling and designCheminformatics and quantitative structure-activity relationships
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Publications (11)

|Jun 15, 2026
Endothelial c-IAP2 loss amplifies P2X7 receptor-driven inflammation and worsens schistosomiasis-associated pulmonary hypertension.

|Jun 12, 2026
Synthesis of Methoxylated Benzoxanthones as Drug Metabolites of Antischistosomal Schistodiones-A Limited Environmental Risk.

|Apr 30, 2025
Targeting Apicomplexan Parasites: Structural and Functional Characterization of <i>Cryptosporidium</i> Thioredoxin Reductase as a Novel Drug Target.

Federica Gabriele, Jala A Bogard, Marta Palerma

|Nov 27, 2024
Regioselective Synthesis of Potential Non-Quinonoid Prodrugs of Plasmodione: Antiparasitic Properties Against Two Hemoglobin-Feeding Parasites and Drug Metabolism Studies.

Elena Cesar-Rodo, Baptiste Dupouy, Cécile Häberli

|Sep 09, 2024
The "Doorstop Pocket" In Thioredoxin Reductases─An Unexpected Druggable Regulator of the Catalytic Machinery.

Matteo Ardini, Sammy Y Aboagye, Valentina Z Petukhova

|Jun 22, 2023
Non-covalent inhibitors of thioredoxin glutathione reductase with schistosomicidal activity in vivo.

Valentina Z Petukhova, Sammy Y Aboagye, Matteo Ardini

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Frequent Collaborators

6 joint publications

Pavel A Petukhov

5 joint publications

Francesco Angelucci

3 joint publications

Gregory R J Thatcher

3 joint publications

Samuel Yaw Aboagye