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Tom J Brett

4PUBLICATIONS

1CO-AUTHORS

Biomolecular modelling and designMedical infection agents (incl. prions)Neurology and neuromuscular diseases

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Publications (4)

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|Jan 09, 2025

Biophysical mapping of TREM2-ligand interactions reveals shared surfaces for engagement of multiple Alzheimer's disease ligands.

Jessica A Greven, Joshua R Wydra, Rory A Greer

|Sep 24, 2024

Biophysical mapping of TREM2-ligand interactions reveals shared surfaces for engagement of multiple Alzheimer's disease ligands.

Jessica A Greven, Joshua R Wydra, Rory A Greer

|Oct 22, 2020

Functional insights from biophysical study of TREM2 interactions with apoE and Aβ<sub>1-42</sub>.

Daniel L Kober, Melissa D Stuchell-Brereton, Colin E Kluender

|Dec 21, 2016

Neurodegenerative disease mutations in TREM2 reveal a functional surface and distinct loss-of-function mechanisms.

Daniel L Kober, Jennifer M Alexander-Brett, Celeste M Karch

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Frequent Collaborators

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Celeste M Karch

Frequent Collaborators

1 joint publications

Celeste M Karch

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