Laurence H Pearl

18PUBLICATIONS
48CO-AUTHORS
Cancer diagnosisRadiation therapyMolecular targetsGenome structure and regulationResidential client care
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Publications (18)

|Sep 21, 2026
PUM3 is an essential suppressor of replication stress in homologous recombination deficient breast cancer.

|Jul 02, 2025
The human RIF1-Long isoform interacts with BRCA1 to promote recombinational fork repair under DNA replication stress.

Qianqian Dong, Matthew Day, Yuichiro Saito

|Jul 08, 2024
Identifying actionable synthetically lethal cancer gene pairs using mutual exclusivity.

Sarah K Wooller, Laurence H Pearl, Frances M G Pearl

|Feb 27, 2024
TopBP1 utilises a bipartite GINS binding mode to support genome replication.

Matthew Day, Bilal Tetik, Milena Parlak

|Nov 29, 2022
HSP90-CDC37-PP5 forms a structural platform for kinase dephosphorylation.

Jasmeen Oberoi, Xavi Aran Guiu, Emily A Outwin

|Nov 18, 2022
Structural basis for the inactivation of cytosolic DNA sensing by the vaccinia virus.

Angel Rivera-Calzada, Raquel Arribas-Bosacoma, Alba Ruiz-Ramos

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Frequent Collaborators

11 joint publications

Antony W Oliver

4 joint publications

Matthew Day

3 joint publications

Oscar Llorca

2 joint publications

Frances Mg Pearl