Jacob P Mahoney

6PUBLICATIONS
9CO-AUTHORS
Medical virologyBiologically active moleculesCellular nervous systemMolecular targets
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Publications (6)

|Jun 24, 2026
3-Hydroxypyrimidine-2,4-dione derivatives as monkeypox virus resolvase (Mpr) inhibitors.

|Jun 18, 2026
Discovery and characterization of a hydroxypyridone-3-carboxamide analog as an antiviral lead against orthopoxviruses.

|Dec 22, 2025
1-Hydroxy-1,8-napthyridinone (DHN) Analogs Potently Inhibit Monkeypox Virus Resolvase (Mpr).

Samuel Offei, Jacob P Mahoney, Ziyue Wang

|Jun 19, 2025
Discovery of Small-Molecule Orthopoxvirus Resolvase Inhibitors with Antiviral Activity.

Jacob P Mahoney, Samuel Offei, Anil Pant

|Feb 14, 2024
The co-receptor Tetraspanin12 directly captures Norrin to promote ligand-specific β-catenin signaling.

Elise S Bruguera, Jacob P Mahoney, William I Weis

|Aug 23, 2022
PI(4,5)P2-stimulated positive feedback drives the recruitment of Dishevelled to Frizzled in Wnt-β-catenin signaling.

Jacob P Mahoney, Elise S Bruguera, Mansi Vasishtha

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Frequent Collaborators

4 joint publications

Zhengqiang Wang

2 joint publications

Elise S Bruguera

2 joint publications

William I Weis

1 joint publications

Hideki Aihara