Kryštof Škach

4PUBLICATIONS
18CO-AUTHORS
Molecular targetsCheminformatics and quantitative structure-activity relationships
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Publications (4)

|Jul 12, 2025
Discovery of PXR Antagonist MI891 and PXR Degrader MI1013 and Their Roles in Hepatic Gene Regulation.

Rajamanikkam Kamaraj, Ivana Mejdrová, Maria Krutakova

|Feb 06, 2025
The hypolipidemic effect of MI-883, the combined CAR agonist/ PXR antagonist, in diet-induced hypercholesterolemia model.

Jan Dusek, Ivana Mejdrová, Klára Dohnalová

|Aug 03, 2023
Inhibition of FLT3-ITD Kinase in Acute Myeloid Leukemia by New Imidazo[1,2-b]pyridazine Derivatives Identified by Scaffold Hopping.

Petra Břehová, Eva Řezníčková, Kryštof Škach

|Feb 09, 2023
Discovery of Novel Human Constitutive Androstane Receptor Agonists with the Imidazo[1,2-a]pyridine Structure.

Ivana Mejdrová, Jan Dušek, Kryštof Škach

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