John Silke

61PUBLICATIONS
252CO-AUTHORS
Molecular targetsMedical infection agents (incl. prions)Medical devicesTissue engineeringHaematological tumours
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Publications (61)

|Sep 02, 2026
MAP3K14 (NIK) synonymous variants drive altered splicing to activate NF-κB in mature B-cell malignancies.

|Jun 10, 2026
Infection-induced glucose starvation triggers NINJ1-dependent macrophage lysis and Candida escape.

|May 29, 2026
The benchmarking and application of tag-degraders in vivo to validate therapeutic targets.

|May 12, 2026
The transmembrane domain structure of TNFR1 suppresses ligand-independent autoactivation but is not required for TNF-induced signaling.

|Feb 03, 2026
The kinase domain of RIPK3 tunes its scaffolding functions.

Shene Chiou, Christopher R Horne, Komal M Patel

|Jan 19, 2026
Expanding the toolbox to develop IAP-based degraders of TEAD transcription factors.

Nishma Gupta, Nicole Trainor, Mona Radwan

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Frequent Collaborators

11 joint publications

James M Murphy

10 joint publications

Joanne M Hildebrand

9 joint publications

Najoua Lalaoui

7 joint publications

Holly Anderton