Jack D Scott

5PUBLICATIONS
26CO-AUTHORS
Medical molecular engineering of nucleic acids and proteinsCharacterisation of biological macromoleculesBiologically active moleculesProteins and peptides
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Publications (5)

|Feb 22, 2024
Structure Guided Discovery of Novel Pan Metallo-β-Lactamase Inhibitors with Improved Gram-Negative Bacterial Cell Penetration.

Shuzhi Dong, Zhiqiang Zhao, Haiqun Tang

|Oct 27, 2023
Synthesis of DNA-Encoded Macrocyclic Peptides via Nitrile-Aminothiol Click Reaction.

Lijun Fan, Yang Yu, Charles Jayne

|Dec 08, 2022
Discovery and Optimization of Potent, Selective, and Brain-Penetrant 1-Heteroaryl-1<i>H</i>-Indazole LRRK2 Kinase Inhibitors for the Treatment of Parkinson's Disease.

David A Candito, Vladimir Simov, Anmol Gulati

|Aug 06, 2021
Optimization of brain-penetrant picolinamide derived leucine-rich repeat kinase 2 (LRRK2) inhibitors.

Anmol Gulati, Charles S Yeung, Blair Lapointe

|Mar 01, 2017
Discovery of a 3-(4-Pyrimidinyl) Indazole (MLi-2), an Orally Available and Selective Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitor that Reduces Brain Kinase Activity.

Jack D Scott, Duane E DeMong, Thomas J Greshock

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Frequent Collaborators

2 joint publications

Anmol Gulati

2 joint publications

Ellen C Minnihan

1 joint publications

John M Sanders

1 joint publications

Charles S Yeung