Antje K Rottner

5PUBLICATIONS
47CO-AUTHORS
Molecular evolutionGenome structure and regulationMolecular targetsEpigenetics (incl. genome methylation and epigenomics)
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Publications (5)

|Sep 06, 2023
A Type II-B Cas9 nuclease with minimized off-targets and reduced chromosomal translocations in vivo.

Burcu Bestas, Sandra Wimberger, Dmitrii Degtev

|Jan 12, 2023
Loss of RREB1 in pancreatic beta cells reduces cellular insulin content and affects endocrine cell gene expression.

Katia K Mattis, Nicole A J Krentz, Christoph Metzendorf

|Dec 21, 2022
A genome-wide CRISPR screen identifies CALCOCO2 as a regulator of beta cell function influencing type 2 diabetes risk.

Antje K Rottner, Yingying Ye, Elena Navarro-Guerrero

|May 13, 2020
A CRISPR/Cas9 genome editing pipeline in the EndoC-βH1 cell line to study genes implicated in beta cell function.

Antje K Grotz, Fernando Abaitua, Elena Navarro-Guerrero

|Nov 03, 2019
Loss of ZnT8 function protects against diabetes by enhanced insulin secretion.

Om Prakash Dwivedi, Mikko Lehtovirta, Benoit Hastoy

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