Mihirbaran Mandal

8PUBLICATIONS
18CO-AUTHORS
Proteins and peptidesMedical molecular engineering of nucleic acids and proteinsPharmacogenomicsCheminformatics and quantitative structure-activity relationshipsInfectious agents
Featured researcher

Get your video featured.

JoVEPublish with JoVE
Journal

Publications (8)

|Mar 18, 2026
N‑Alkyl and N‑Aryl Aminopyrazole Spirocarbamates: A Two-Pronged Lead Optimization Strategy to Identify Orally Bioavailable Plasma Kallikrein Inhibitors.

Rohan R Merchant, Natalia Chernyak, Jovan A Lopez

|Feb 22, 2024
Structure Guided Discovery of Novel Pan Metallo-β-Lactamase Inhibitors with Improved Gram-Negative Bacterial Cell Penetration.

Shuzhi Dong, Zhiqiang Zhao, Haiqun Tang

|Dec 08, 2022
Rapid Evolution of a Fragment-like Molecule to Pan-Metallo-Beta-Lactamase Inhibitors: Initial Leads toward Clinical Candidates.

Mihirbaran Mandal, Li Xiao, Weidong Pan

|Mar 29, 2022
Lead Optimization to Advance Protease-Activated Receptor-1 Antagonists in Early Discovery.

Mihirbaran Mandal, Maria Madeira, Rupesh P Amin

|Aug 14, 2020
Generation of Leads for γ-Secretase Modulation.

Mihirbaran Mandal, Alexei Buevich, John P Caldwell

|Nov 03, 2018
Overcoming Time-Dependent Inhibition (TDI) of Cytochrome P450 3A4 (CYP3A4) Resulting from Bioactivation of a Fluoropyrimidine Moiety.

Mihirbaran Mandal, Kaushik Mitra, Diane Grotz

Pageof 2

Frequent Collaborators

5 joint publications

Alexei V Buevich

2 joint publications

Alan Cheng

1 joint publications

Scott S Walker

1 joint publications

Rohan R Merchant