Jean-Philippe Gagné

7PUBLICATIONS
30CO-AUTHORS
Cancer therapy (excl. chemotherapy and radiation therapy)Molecular targetsCell development, proliferation and deathEpigenetics (incl. genome methylation and epigenomics)Predictive and prognostic markers
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Publications (7)

|Nov 29, 2025
Nucleoplasmic Lamin A/C controls replication fork restart upon stress by modulating local H3K9me3 and ADP-ribosylation levels.

Veronica Cherdyntseva, Joanna Paulson, Daniel González-Acosta

|Jan 25, 2025
CHD6 has poly(ADP-ribose)- and DNA-binding domains and regulates PARP1/2-trapping inhibitor sensitivity via abasic site repair.

Luc Provencher, Wilson Nartey, Peter M Brownlee

|Mar 18, 2024
Poly(ADP-ribose) mediates bioenergetic defects and redox imbalance in neurons following oxygen and glucose deprivation.

M Iqbal Hossain, Jun Hee Lee, Jean-Philippe Gagné

|Mar 11, 2021
Zinc finger protein E4F1 cooperates with PARP-1 and BRG1 to promote DNA double-strand break repair.

Céline Moison, Jalila Chagraoui, Marie-Christine Caron

|Nov 02, 2020
The prefoldin complex stabilizes the von Hippel-Lindau protein against aggregation and degradation.

Franck Chesnel, Anne Couturier, Adrien Alusse

|Jun 09, 2020
The SARS-CoV-2 conserved macrodomain is a mono-ADP-ribosylhydrolase.

Yousef M O Alhammad, Maithri M Kashipathy, Anuradha Roy

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Frequent Collaborators

3 joint publications

Guy G Poirier

1 joint publications

Yousef M O Alhammad

1 joint publications

Anuradha Roy

1 joint publications

Kevin P Battaile