Megan Jr Yeo

6PUBLICATIONS
39CO-AUTHORS
Molecular targetsCarbon capture engineering (excl. sequestration)Biologically active moleculesReaction engineering (excl. nuclear reactions)Biomolecular modelling and design
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Publications (6)

|Feb 12, 2025
Converging mechanism of UM171 and KBTBD4 neomorphic cancer mutations.

Xiaowen Xie, Olivia Zhang, Megan J R Yeo

|Feb 12, 2025
UM171 glues asymmetric CRL3-HDAC1/2 assembly to degrade CoREST corepressors.

Megan J R Yeo, Olivia Zhang, Xiaowen Xie

|May 27, 2024
Asymmetric Engagement of Dimeric CRL3 <sup>KBTBD4</sup> by the Molecular Glue UM171 Licenses Degradation of HDAC1/2 Complexes.

Megan Jr Yeo, Olivia Zhang, Xiaowen Xie

|May 27, 2024
KBTBD4 Cancer Hotspot Mutations Drive Neomorphic Degradation of HDAC1/2 Corepressor Complexes.

Xiaowen Xie, Olivia Zhang, Megan J R Yeo

|May 04, 2022
Profiling the Landscape of Drug Resistance Mutations in Neosubstrates to Molecular Glue Degraders.

Pallavi M Gosavi, Kevin C Ngan, Megan J R Yeo

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