Gerald T Nepom

6PUBLICATIONS
42CO-AUTHORS
Applied immunology (incl. antibody engineering, xenotransplantation and t-cell therapies)Autoimmunity
Featured researcher

Get your video featured.

JoVEPublish with JoVE
Journal

Publications (6)

|Mar 12, 2025
Early expansion of TIGIT+PD1+ effector memory CD4 T cells via agonistic effect of alefacept in new-onset type 1 diabetes.

Lauren E Higdon, Laura A Cooney, Elisavet Serti

|Oct 02, 2023
A first-in-human, open-label Phase 1b and a randomised, double-blind Phase 2a clinical trial in recent-onset type 1 diabetes with AG019 as monotherapy and in combination with teplizumab.

Chantal Mathieu, Alice Wiedeman, Karen Cerosaletti

|Aug 29, 2019
Discriminative T cell recognition of cross-reactive islet-antigens is associated with HLA-DQ8 transdimer-mediated autoimmune diabetes.

I-Ting Chow, Theresa J Gates, George K Papadopoulos

|Jan 27, 2019
Abatacept Targets T Follicular Helper and Regulatory T Cells, Disrupting Molecular Pathways That Regulate Their Proliferation and Maintenance.

Simon Glatigny, Barbara Höllbacher, Samantha J Motley

|Jun 02, 2017
Single-Cell RNA Sequencing Reveals Expanded Clones of Islet Antigen-Reactive CD4+ T Cells in Peripheral Blood of Subjects with Type 1 Diabetes.

Karen Cerosaletti, Fariba Barahmand-Pour-Whitman, Junbao Yang

|May 28, 2017
Antigen-Specific T Cell Analysis Reveals That Active Immune Responses to β Cell Antigens Are Focused on a Unique Set of Epitopes.

Junbao Yang, Xiaomin Wen, Hengyu Xu

Pageof 1

Frequent Collaborators

3 joint publications

Cate Speake

2 joint publications

Elisavet Serti

2 joint publications

Carla J Greenbaum

2 joint publications

S Alice Long