Manuel A F V Gonçalves

11PUBLICATIONS
13CO-AUTHORS
Reaction engineering (excl. nuclear reactions)Micro-manipulationPowder and particle technologyElectrochemical energy storage and conversionGene and molecular therapy
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Publications (11)

|Apr 29, 2025
Donor insertion into CX3CR1 allows epigenetic modulation of a constitutive promoter on hematopoietic stem cells and its activation upon myeloid differentiation.

Iris Ramos-Hernández, Carla Fuster-García, Araceli Aguilar-González

|Dec 10, 2024
Precision genome editing using combinatorial viral vector delivery of CRISPR-Cas9 nucleases and donor DNA constructs.

Zhen Li, Xiaoling Wang, Josephine M Janssen

|Feb 07, 2024
Selection-free precise gene repair using high-capacity adenovector delivery of advanced prime editing systems rescues dystrophin synthesis in DMD muscle cells.

Qian Wang, Sabrina Capelletti, Jin Liu

|Mar 17, 2023
Precise homology-directed installation of large genomic edits in human cells with cleaving and nicking high-specificity Cas9 variants.

Qian Wang, Jin Liu, Josephine M Janssen

|Jul 01, 2022
Large-scale genome editing based on high-capacity adenovectors and CRISPR-Cas9 nucleases rescues full-length dystrophin synthesis in DMD muscle cells.

Francesca Tasca, Marcella Brescia, Qian Wang

|Oct 20, 2021
Broadening the reach and investigating the potential of prime editors through fully viral gene-deleted adenoviral vector delivery.

Qian Wang, Jin Liu, Josephine M Janssen

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Frequent Collaborators

2 joint publications

Rob C Hoeben

1 joint publications

Xiaoyu Chen

1 joint publications

Remko Goossens

1 joint publications

Marlinde L van den Boogaard