Murray Ch Clarke

4PUBLICATIONS
0CO-AUTHORS
Cardiology (incl. cardiovascular diseases)Immunogenetics (incl. genetic immunology)Applied immunology (incl. antibody engineering, xenotransplantation and t-cell therapies)Innate immunity
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Publications (4)

|Jun 13, 2023
Thrombin-activated interleukin-1α drives atherogenesis, but also promotes vascular smooth muscle cell proliferation and collagen production.

Laura C Burzynski, Alejandra Morales-Maldonado, Amanda Rodgers

|Sep 29, 2022
The common IL1A single nucleotide polymorphism rs17561 is a hypomorphic mutation that significantly reduces interleukin-1α release from human blood cells.

Kimberley A Wiggins, Katerina Pyrillou, Melanie Humphry

|May 25, 2020
Cell surface IL-1α trafficking is specifically inhibited by interferon-γ, and associates with the membrane via IL-1R2 and GPI anchors.

Julie N E Chan, Melanie Humphry, Lauren Kitt

|Mar 28, 2019
IL-1α cleavage by inflammatory caspases of the noncanonical inflammasome controls the senescence-associated secretory phenotype.

Kimberley A Wiggins, Aled J Parry, Liam D Cassidy

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