Haruhide Kimura

10PUBLICATIONS
7CO-AUTHORS
Animal systematics and taxonomyNutritional epidemiologyChemotherapyGene and molecular therapyEpigenetics (incl. genome methylation and epigenomics)
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Publications (10)

|Jun 25, 2024
Orexin receptor 2 agonist activates diaphragm and genioglossus muscle through stimulating inspiratory neurons in the pre-Bötzinger complex, and phrenic and hypoglossal motoneurons in rodents.

Ryuji Yamada, Tatsuki Koike, Masanori Nakakariya

|Mar 19, 2023
Orexin 2 receptor-selective agonist danavorexton (TAK-925) promotes wakefulness in non-human primates and healthy individuals.

Rebecca Evans, Haruhide Kimura, Masato Nakashima

|Jan 31, 2023
Diurnal Fluctuations of Orexin-A and -B in Cynomolgus Monkey Cerebrospinal Fluid Determined by a Novel Analytical Method Using Antiadsorptive Additive Treatment Followed by Nanoflow Liquid Chromatography-High-Resolution Mass Spectrometry.

Naohiro Narita, Ryuji Yamada, Masaaki Kakehi

|Jan 21, 2022
Investigating the Therapeutic Potential of LSD1 Enzyme Activity-Specific Inhibition by TAK-418 for Social and Memory Deficits in Rodent Disease Models.

Rina Baba, Satoru Matsuda, Ryota Maeda

|Mar 13, 2021
LSD1 enzyme inhibitor TAK-418 unlocks aberrant epigenetic machinery and improves autism symptoms in neurodevelopmental disorder models.

Rina Baba, Satoru Matsuda, Yuuichi Arakawa

|Jan 29, 2020
T-495, a novel low cooperative M1 receptor positive allosteric modulator, improves memory deficits associated with cholinergic dysfunction and is characterized by low gastrointestinal side effect risk.

Takao Mandai, Yuu Sako, Emi Kurimoto

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Frequent Collaborators

2 joint publications

Kazunori Suzuki

2 joint publications

Rina Baba

2 joint publications

Satoru Matsuda

1 joint publications

Tatsuya Ando