Chu-Yi Yu

12PUBLICATIONS
9CO-AUTHORS
Medical devicesBiologically active moleculesGlycoconjugatesCheminformatics and quantitative structure-activity relationshipsMolecular medicine
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Publications (12)

|Jul 31, 2026
4-Dehydroxymethyl-4-C-biphenyl-DAB derivatives: introduction of a biphenyl group at the C4 position shifts the binding selectivity, resulting in improved affinity for lysosomal acid β-glucocerebrosidase.

|Jun 20, 2026
Synthesis of Polyhydroxylated Dihydro-Oxazines, Their Reactivity Studies, and Applications in the Construction of 1,2-Oxazinane Iminosugar Library with Bioactivities.

|Feb 20, 2025
C-2 fluorinated castanospermines as potent and specific α-glucosidase inhibitors: synthesis and structure-activity relationship study.

Yi-Xian Li, Ming Zhang, Yuna Shimadate

|Apr 11, 2023
Design and synthesis of iso-allo-DNJ and L-isoDALDP derivatives: pursuit of potent and selective inhibitors of α-glucosidase.

Lin-Feng Yang, Ming Zhang, Yuna Shimadate

|Mar 14, 2023
Design, synthesis and glycosidase inhibition of DAB derivatives with C-4 peptide and dipeptide branches.

Dong Zi, Yuna Shimadate, Jun-Zhe Wang

|Jul 15, 2022
Introduction of C-alkyl branches to L-iminosugars changes their active site binding orientation.

Atsushi Kato, Izumi Nakagome, Kosuke Yoshimura

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Frequent Collaborators

10 joint publications

Atsushi Kato

6 joint publications

Yi-Xian Li

3 joint publications

George W J Fleet

2 joint publications

Robert J Nash