Henrik Möbitz

5PUBLICATIONS
11CO-AUTHORS
Theory and design of materialsMedical molecular engineering of nucleic acids and proteinsBasic pharmacologyPharmaceutical delivery technologiesGene and molecular therapy
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Publications (5)

|May 15, 2024
Nonclassical Zwitterions as a Design Principle to Reduce Lipophilicity without Impacting Permeability.

Henrik Möbitz, Birger Dittrich, Stephane Rodde

|Apr 24, 2024
Discovery of WRN inhibitor HRO761 with synthetic lethality in MSI cancers.

Stephane Ferretti, Jacques Hamon, Ruben de Kanter

|Nov 21, 2023
Design Principles for Balancing Lipophilicity and Permeability in beyond Rule of 5 Space.

Henrik Möbitz

|Sep 07, 2022
Paradoxical Increase of Permeability and Lipophilicity with the Increasing Topological Polar Surface Area within a Series of PRMT5 Inhibitors.

Upendra Argikar, Markus Blatter, Dallas Bednarczyk

|Feb 23, 2022
Discovery of MAP855, an Efficacious and Selective MEK1/2 Inhibitor with an ATP-Competitive Mode of Action.

Ramulu Poddutoori, Kimberly Aardalen, Kiran Aithal

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Frequent Collaborators

1 joint publications

Susanta Samajdar

1 joint publications

Klemens Hoegenauer

1 joint publications

Carole Pissot Soldermann

1 joint publications

Ruben de Kanter