Adam C Oken

8PUBLICATIONS
30CO-AUTHORS
Autonomic nervous systemProteins and peptidesMolecular targetsSensory processes, perception and performance
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Publications (8)

|Apr 17, 2026
A brain-penetrant P2X7R antagonist mitigates Alzheimer's disease pathology.

|Sep 15, 2025
A polycyclic scaffold identified by structure-based drug design effectively inhibits the human P2X7 receptor.

Adam C Oken, Andreea L Turcu, Eva Tzortzini

|Sep 12, 2025
Subtype-specific structural features of the hearing loss-associated human P2X2 receptor.

Franka G Westermann, Adam C Oken, Philip K E Granith

|Jan 17, 2025
Human P2X4 receptor gating is modulated by a stable cytoplasmic cap and a unique allosteric pocket.

Haoyuan Shi, Ismayn A Ditter, Adam C Oken

|Oct 04, 2024
P2X7 receptors exhibit at least three modes of allosteric antagonism.

Adam C Oken, Ismayn A Ditter, Nicolas E Lisi

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