Brian A Lanman

6PUBLICATIONS
25CO-AUTHORS
Molecular targetsCharacterisation of biological macromoleculesMedical infection agents (incl. prions)
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Publications (6)

|Jul 14, 2026
Expanding Addressable KRAS Mutations through the Structure- and Property-Based Design of Dual-State (GDP/GTP), Reversible Pan-KRAS Inhibitors.

|Aug 21, 2025
LYMTACs:chimeric small molecules repurpose lysosomal membrane proteins for target protein relocalization and degradation.

Dhanusha A Nalawansha, Georgios Mazis, Gitte Husemoen

|Mar 27, 2025
Discovery of AMG 193, an MTA-Cooperative PRMT5 Inhibitor for the Treatment of MTAP-Deleted Cancers.

Liping H Pettus, Matthew Bourbeau, Nuria A Tamayo

|Feb 11, 2025
Identification of Structurally Novel KRASG12C Inhibitors through Covalent DNA-Encoded Library Screening.

David Huang, Francesco Manoni, Zhen Sun

|Sep 30, 2022
Addressing Atropisomerism in the Development of Sotorasib, a Covalent Inhibitor of KRAS G12C: Structural, Analytical, and Synthetic Considerations.

Brian A Lanman, Andrew T Parsons, Stephan G Zech

|Dec 11, 2019
Discovery of a Covalent Inhibitor of KRASG12C (AMG 510) for the Treatment of Solid Tumors.

Brian A Lanman, Jennifer R Allen, John G Allen

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Frequent Collaborators

2 joint publications

Ryan P Wurz

2 joint publications

Victor J Cee

2 joint publications

Liping H Pettus

2 joint publications

Nuria A Tamayo