Christopher J Helal

12PUBLICATIONS
25CO-AUTHORS
Chemical engineering designBiologically active moleculesBiomolecular modelling and designCharacterisation of biological macromoleculesProcess control and simulation
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Publications (12)

|Jun 07, 2024
Discovery of Clinical Candidate PF-06648671: A Potent γ-Secretase Modulator for the Treatment of Alzheimer's Disease.

Martin Pettersson, Douglas S Johnson, John M Humphrey

|Oct 09, 2019
High-Throughput Ligand Screening Enables the Enantioselective Conjugate Borylation of Cyclobutenones to Access Synthetically Versatile Tertiary Cyclobutylboronates.

Helen A Clement, Michele Boghi, Rory M McDonald

|Apr 03, 2019
Synthetic Approaches to the New Drugs Approved During 2017.

Andrew C Flick, Carolyn A Leverett, Hong X Ding

|Nov 16, 2018
Discovery and Lead Optimization of Atropisomer D1 Agonists with Reduced Desensitization.

Jennifer E Davoren, Deane Nason, Jotham Coe

|Mar 03, 2018
Discovery of Trifluoromethyl Glycol Carbamates as Potent and Selective Covalent Monoacylglycerol Lipase (MAGL) Inhibitors for Treatment of Neuroinflammation.

Laura A McAllister, Christopher R Butler, Scot Mente

|Jan 27, 2018
A platform for automated nanomole-scale reaction screening and micromole-scale synthesis in flow.

Damith Perera, Joseph W Tucker, Shalini Brahmbhatt

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Frequent Collaborators

3 joint publications

Christopher J O'Donnell

2 joint publications

John M Humphrey

2 joint publications

Christopher W Am Ende

2 joint publications

William Farrell