Shiv K Gupta

8PUBLICATIONS
57CO-AUTHORS
Gene and molecular therapyMolecular targetsPharmacogenomics
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Publications (8)

|Jul 01, 2025
Preclinical Modeling of Navtemadlin Pharmacokinetics, Pharmacodynamics, and Efficacy in IDH-Wild-type Glioblastoma.

Rachael A Vaubel, Wenjuan Zhang, Ju-Hee Oh

|Oct 23, 2024
DNA-PK Inhibition Shows Differential Radiosensitization in Orthotopic GBM PDX Models Based on DDR Pathway Deficits.

Sonja Dragojevic, Emily J Smith, Michael S Regan

|Jun 21, 2024
ATM inhibition exploits checkpoint defects and ATM-dependent double strand break repair in TP53-mutant glioblastoma.

Daniel J Laverty, Shiv K Gupta, Gary A Bradshaw

|May 14, 2024
Bystander Effects, Pharmacokinetics, and Linker-Payload Stability of EGFR-Targeting Antibody-Drug Conjugates Losatuxizumab Vedotin and Depatux-M in Glioblastoma Models.

Sonia Jain, Jessica I Griffith, Kendra A Porath

|Feb 14, 2024
Aberrant ATM signaling and homology-directed DNA repair as a vulnerability of p53-mutant GBM to AZD1390-mediated radiosensitization.

Jiajia Chen, Daniel J Laverty, Surabhi Talele

|Jan 15, 2024
Differential Distribution of the DNA-PKcs Inhibitor Peposertib Selectively Radiosensitizes Patient-derived Melanoma Brain Metastasis Xenografts.

Jianxiong Ji, Sonja Dragojevic, Cameron M Callaghan

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