Aochiu Chen

8PUBLICATIONS
23CO-AUTHORS
Medical molecular engineering of nucleic acids and proteinsBiomolecular modelling and designCheminformatics and quantitative structure-activity relationshipsCatalysis and mechanisms of reactionsEnzymes
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Publications (8)

|Apr 07, 2026
Predicting Aberrant Fc-fusion Protein Pharmacokinetics from In Silico Structural Properties and Physiologically Based Pharmacokinetic (PBPK) Modeling.

Danilo Tomasoni, Alessio Paris, Roberto Visintainer

|Jan 16, 2026
Nonspecific Cellular Interactions Are a Key Determinant in the Disposition of Fc-Fused Proteins.

Mark A Bryniarski, Songyu Wang, Aochiu Chen

|Jul 09, 2024
Cryptic Cerulenin Rearrangement in Ketosynthase Covalent Inhibition.

Ziran Jiang, Jeffrey A Chen, Osama G Mohamed

|Oct 03, 2022
Structure and mechanistic analyses of the gating mechanism of elongating ketosynthases.

Jeffrey T Mindrebo, Aochiu Chen, Woojoo E Kim

|Sep 01, 2022
Mechanism-based cross-linking probes capture the Escherichia coli ketosynthase FabB in conformationally distinct catalytic states.

Aochiu Chen, Jeffrey T Mindrebo, Tony D Davis

|May 05, 2022
Enzymology of standalone elongating ketosynthases.

Aochiu Chen, Ziran Jiang, Michael D Burkart

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Frequent Collaborators

6 joint publications

Michael D Burkart

4 joint publications

Tony D Davis

3 joint publications

Joseph P Noel

2 joint publications

Yohei Katsuyama