Leonardo Cheng

6PUBLICATIONS

40CO-AUTHORS

Medical molecular engineering of nucleic acids and proteinsGene and molecular therapyMicro- and nanosystemsBiomaterialsNanomaterials

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Publications (6)

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|Jun 02, 2026

Trivalent ions kinetic-gating for producing high-concentration and shelf-stable plasmid DNA/PEI particles.

|Mar 11, 2026

Biodegradable targeted polymeric mRNA nanoparticles enable in vivo CD19 CAR T cell generation and lead to B cell depletion.

Manav Jain, Savannah E Est-Witte, Sydney R Shannon

|Oct 22, 2025

A multistep platform identifies spleen-tropic lipid nanoparticles for in vivo T cell-targeted delivery of gene-editing proteins.

Xiaoya Lu, Yining Zhu, Christine Wei

|Feb 20, 2025

mRNA lipid nanoparticle-incorporated nanofiber-hydrogel composite generates a local immunostimulatory niche for cancer immunotherapy.

Yining Zhu, Zhi-Cheng Yao, Shuyi Li

|Oct 07, 2024

Machine Learning Elucidates Design Features of Plasmid Deoxyribonucleic Acid Lipid Nanoparticles for Cell Type-Preferential Transfection.

Leonardo Cheng, Yining Zhu, Jingyao Ma

|Dec 18, 2023

Machine Learning Elucidates Design Features of Plasmid DNA Lipid Nanoparticles for Cell Type-Preferential Transfection.

Leonardo Cheng, Yining Zhu, Jingyao Ma

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Frequent Collaborators

Hai-Quan Mao

Yining Zhu

Jinghan Lin

Jonathan P Schneck

Xiang Liu

Christine Wei

Kailei D Goodier

Jiayuan Kong

Xiaoya Lu

Tine Curk

Frequent Collaborators

Hai-Quan Mao

Yining Zhu

Jinghan Lin

Jonathan P Schneck