Leonardo Cheng

6PUBLICATIONS
40CO-AUTHORS
Medical molecular engineering of nucleic acids and proteinsGene and molecular therapyMicro- and nanosystemsBiomaterialsNanomaterials
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Publications (6)

|Jun 02, 2026
Trivalent ions kinetic-gating for producing high-concentration and shelf-stable plasmid DNA/PEI particles.

|Mar 11, 2026
Biodegradable targeted polymeric mRNA nanoparticles enable in vivo CD19 CAR T cell generation and lead to B cell depletion.

Manav Jain, Savannah E Est-Witte, Sydney R Shannon

|Oct 22, 2025
A multistep platform identifies spleen-tropic lipid nanoparticles for in vivo T cell-targeted delivery of gene-editing proteins.

Xiaoya Lu, Yining Zhu, Christine Wei

|Feb 20, 2025
mRNA lipid nanoparticle-incorporated nanofiber-hydrogel composite generates a local immunostimulatory niche for cancer immunotherapy.

Yining Zhu, Zhi-Cheng Yao, Shuyi Li

|Oct 07, 2024
Machine Learning Elucidates Design Features of Plasmid Deoxyribonucleic Acid Lipid Nanoparticles for Cell Type-Preferential Transfection.

Leonardo Cheng, Yining Zhu, Jingyao Ma

|Dec 18, 2023
Machine Learning Elucidates Design Features of Plasmid DNA Lipid Nanoparticles for Cell Type-Preferential Transfection.

Leonardo Cheng, Yining Zhu, Jingyao Ma

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Frequent Collaborators

4 joint publications

Hai-Quan Mao

3 joint publications

Yining Zhu

3 joint publications

Jinghan Lin

2 joint publications

Jonathan P Schneck