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Sean W Fanning

16PUBLICATIONS

78CO-AUTHORS

Biologically active moleculesBiodiscoveryMolecular targetsCancer therapy (excl. chemotherapy and radiation therapy)Applied immunology (incl. antibody engineering, xenotransplantation and t-cell therapies)

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Publications (16)

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|Feb 18, 2026

Allosteric Induction of Estrogen Receptor Ligand Binding Domain Tetramerization by a Distinct Complete Estrogen Receptor Antagonist.

Emma C Fink, Reena Chawla, Govinda R Hancock

|Aug 14, 2025

Benzestrol Isomer Stereochemistry Determines the Distinct Estrogenic Activities and Conformations of the Eight Isomers When Bound to Estrogen Receptor α.

Yingwei Hou, Jerome C Nwachukwu, Kathryn Carlson

|Aug 12, 2025

SOX2 utilizes FOXA1 as a heteromeric transcriptional partner to drive proliferation in therapy-resistant prostate cancer.

John T Phoenix, Audris Budreika, Devin A Schmeck

|Jun 16, 2025

Discovery of Palazestrant (OP-1250), a Potent and Orally Bioavailable Complete Estrogen Receptor Antagonist (CERAN) and Selective Estrogen Receptor Degrader (SERD).

Raymond A Ng, Susanna Barratt, Alison Parisian

|Jun 04, 2025

Inhibition of NR2F2 restores hormone therapy response to endocrine refractory breast cancers.

Yanyan Cai, Peihua Zhao, Fan Wu

|Feb 13, 2025

Rational Design and Optimization of a Potent IDO1 Proteolysis Targeting Chimera (PROTAC).

Paige J Monsen, Prashant V Bommi, Arabela A Grigorescu

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Frequent Collaborators

7 joint publications

Geoffrey L Greene

3 joint publications

Emad Tajkhorshid

3 joint publications

Emma Fink

3 joint publications

Sarat Chandarlapaty

3 joint publications

John A Katzenellenbogen

2 joint publications

Govinda R Hancock

2 joint publications

Christopher G Mayne

2 joint publications

Benita S Katzenellenbogen

2 joint publications

Myles Brown

1 joint publications

Bradley Green

Frequent Collaborators

7 joint publications

Geoffrey L Greene

3 joint publications

Emad Tajkhorshid

3 joint publications

Emma Fink

3 joint publications

Sarat Chandarlapaty

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