William Lehman

9PUBLICATIONS
23CO-AUTHORS
Cancer diagnosisDynamics, vibration and vibration controlEnergy generation, conversion and storage (excl. chemical and electrical)Cancer therapy (excl. chemotherapy and radiation therapy)Cardiology (incl. cardiovascular diseases)
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Publications (9)

|Apr 12, 2024
Myosin's powerstroke transitions define atomic scale movement of cardiac thin filament tropomyosin.

Michael J Rynkiewicz, Matthew C Childers, Olga E Karpicheva

|May 30, 2023
Troponin-I-induced tropomyosin pivoting defines thin-filament function in relaxed and active muscle.

William Lehman, Michael J Rynkiewicz

|Jan 12, 2023
Conformational changes linked to ADP release from human cardiac myosin bound to actin-tropomyosin.

Matthew H Doran, Michael J Rynkiewicz, David Rasicci

|Dec 02, 2022
Myosin loop-4 is critical for optimal tropomyosin repositioning on actin during muscle activation and relaxation.

Matthew H Doran, Michael J Rynkiewicz, Elumalai Pavadai

|Jul 28, 2021
Loss of crossbridge inhibition drives pathological cardiac hypertrophy in patients harboring the TPM1 E192K mutation.

Lorenzo R Sewanan, Jinkyu Park, Michael J Rynkiewicz

|Oct 02, 2019
The mechanism of thin filament regulation: Models in conflict?

Michael A Geeves, Sherwin S Lehrer, William Lehman

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