Sébastien L Degorce

5PUBLICATIONS
5CO-AUTHORS
Biomolecular modelling and designPowder and particle technologyCheminformatics and quantitative structure-activity relationshipsBiologically active molecules
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Publications (5)

|May 15, 2023
Design of rigid protein-protein interaction inhibitors enables targeting of undruggable Mcl-1.

David Hargreaves, Rodrigo J Carbajo, Michael S Bodnarchuk

|Aug 18, 2020
Discovery of Proteolysis-Targeting Chimera Molecules that Selectively Degrade the IRAK3 Pseudokinase.

Sébastien L Degorce, Omid Tavana, Erica Banks

|Oct 18, 2019
Discovery of a Series of 5-Azaquinazolines as Orally Efficacious IRAK4 Inhibitors Targeting MyD88L265P Mutant Diffuse Large B Cell Lymphoma.

Sébastien L Degorce, Rana Anjum, Andrew Bloecher

|Jan 15, 2019
Tricyclic Indazoles-A Novel Class of Selective Estrogen Receptor Degrader Antagonists.

James S Scott, Andrew Bailey, David Buttar

|Sep 07, 2018
Lowering Lipophilicity by Adding Carbon: One-Carbon Bridges of Morpholines and Piperazines.

Sébastien L Degorce, Michael S Bodnarchuk, Iain A Cumming

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Frequent Collaborators

3 joint publications

James S Scott

1 joint publications

Graeme R Robb

1 joint publications

Omid Tavana

1 joint publications

Rodrigo J Carbajo