Lavleen Mader

7PUBLICATIONS
16CO-AUTHORS
Biomolecular modelling and designProteins and peptidesCharacterisation of biological macromoleculesCheminformatics and quantitative structure-activity relationshipsEnzymes
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Publications (7)

|Apr 30, 2026
Don't Lose Your (War)head: Structure-Activity Relationships of Covalent Warheads as Substrates for GST-Catalyzed Glutathione Conjugation.

|Oct 30, 2025
Discovery of an internal alkyne warhead scaffold for irreversible hTG2 inhibition.

Lavleen K Mader, Namita Maunick, Jessica E Borean

|Mar 31, 2025
Methods for kinetic evaluation of reversible covalent inhibitors from time-dependent IC50 data.

Lavleen K Mader, Jeffrey W Keillor

|Nov 11, 2024
A practical guide for the assay-dependent characterisation of irreversible inhibitors.

Lavleen K Mader, Jessica E Borean, Jeffrey W Keillor

|May 15, 2024
Fitting of kinact and KI Values from Endpoint Pre-incubation IC50 Data.

Lavleen K Mader, Jeffrey W Keillor

|Feb 27, 2023
The war on hTG2: warhead optimization in small molecule human tissue transglutaminase inhibitors.

Lavleen Mader, Sarah K I Watt, Harish R Iyer

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Frequent Collaborators

6 joint publications

Jeffrey W Keillor

2 joint publications

Jessica E Borean

1 joint publications

Martin K Bakht

1 joint publications

John J Hayward