Xavier Declèves

20PUBLICATIONS
30CO-AUTHORS
PharmacogenomicsMolecular targetsCancer therapy (excl. chemotherapy and radiation therapy)Pharmaceutical delivery technologiesEndocrinology
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Publications (20)

|Jul 04, 2025
Prediction of a CLDN18.2 Targeted Antibody Drug Conjugate Pharmacokinetics in Cancer Patients Using PBPK Modeling and Simulation.

Chiara Zunino, Sichen Wang, Yanyan Zhang

|May 15, 2024
Quantitative systems pharmacology modeling of tumor heterogeneity in response to BH3-mimetics using virtual tumors calibrated with cell viability assays.

Thibaud Derippe, Sylvain Fouliard, Xavier Decleves

|Oct 11, 2023
A Minimal PBPK Model for Plasma and Cerebrospinal Fluid Pharmacokinetics of Trastuzumab after Intracerebroventricular Administration in Patients with HER2-Positive Brain Metastatic Localizations.

Alicja Puszkiel, Guilhem Bousquet, Françoise Stanke-Labesque

|Aug 26, 2023
Translation of Monoclonal Antibodies Pharmacokinetics from Animal to Human Using Physiologically Based Modeling in Open Systems Pharmacology (OSP) Suite: A Retrospective Analysis of Bevacizumab.

Blaise Pasquiers, Salih Benamara, Mathieu Felices

|Mar 29, 2023
Phenotyping Indices of CYP450 and P-Glycoprotein in Human Volunteers and in Patients Treated with Painkillers or Psychotropic Drugs.

Léa Darnaud, Clément Delage, Youssef Daali

|Mar 27, 2023
Mechanistic Modeling of the Interplay Between Host Immune System, IL-7 and UCART19 Allogeneic CAR-T Cells in Adult B-cell Acute Lymphoblastic Leukemia.

Thibaud Derippe, Sylvain Fouliard, Ibtissam Marchiq

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Frequent Collaborators

4 joint publications

Salvatore Cisternino

3 joint publications

Nihel Khoudour

2 joint publications

Florence Vorspan

2 joint publications

Vanessa Bloch