Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

David Cappellen

6PUBLICATIONS

41CO-AUTHORS

Molecular targetsRegenerative medicine (incl. stem cells)Predictive and prognostic markersHaematological tumoursEpigenetics (incl. genome methylation and epigenomics)

Featured researcher

Get your video featured.

Publish with JoVE

Featured researcher

Get your video featured.

Publish with JoVE

Publications (6)

Sort by Publication Date:

|Jan 10, 2026

Single-cell multiplex approaches deeply map ON-target CRISPR-genotoxicity and reveal its mitigation by palbociclib and long-term engraftment.

Julian Boutin, Sabrina Fayet, Victor Marin

|Feb 03, 2025

Exploiting metabolic vulnerability in glioblastoma using a brain-penetrant drug with a safe profile.

Audrey Burban, Cloe Tessier, Mathieu Larroquette

|Jul 10, 2023

Cell cycle arrest and p53 prevent ON-target megabase-scale rearrangements induced by CRISPR-Cas9.

G Cullot, J Boutin, S Fayet

|Dec 24, 2021

Positive Association Between Location of Melanoma, Ultraviolet Signature, Tumor Mutational Burden, and Response to Anti-PD-1 Therapy.

Léa Dousset, Florence Poizeau, Caroline Robert

|Sep 28, 2021

Hepatocellular adenoma with a double mutation HNF1A and IDH1 in a patient with Ollier disease.

David Cappellen, Isabelle Catry-Thomas, Claire Castain

|Aug 14, 2021

CRISPR-Cas9 globin editing can induce megabase-scale copy-neutral losses of heterozygosity in hematopoietic cells.

J Boutin, J Rosier, D Cappellen

Pageof 1

Frequent Collaborators

3 joint publications

Julian Boutin

3 joint publications

Jean-Philippe Merlio

3 joint publications

François Moreau-Gaudry

2 joint publications

P Pennamen

2 joint publications

Chloé Thibault

1 joint publications

G Cullot

1 joint publications

Claire Castain

1 joint publications

Paulette Bioulac-Sage

1 joint publications

Léa Dousset

1 joint publications

Florence Poizeau

Frequent Collaborators

3 joint publications

Julian Boutin

3 joint publications

Jean-Philippe Merlio

3 joint publications

François Moreau-Gaudry

2 joint publications

P Pennamen

Top Related Videos

Dual CRISPR-Interference Strategy for Targeting Synthetic Lethal Interactions Between Non-Coding RNAs in Cancer Cells

Dual CRISPR-Interference Strategy for Targeting Synthetic Lethal Interactions Between Non-Coding RNAs in Cancer Cells

Published on : May 30, 2025

Nanoparticle Delivery of an Oligonucleotide Payload in a Glioblastoma Multiforme Animal Model

Nanoparticle Delivery of an Oligonucleotide Payload in a Glioblastoma Multiforme Animal Model

Published on : Sep 27, 2024

Selection-dependent and Independent Generation of CRISPR/Cas9-mediated Gene Knockouts in Mammalian Cells

Selection-dependent and Independent Generation of CRISPR/Cas9-mediated Gene Knockouts in Mammalian Cells

Published on : Jun 16, 2017

See more related videos

Top Related Videos

Dual CRISPR-Interference Strategy for Targeting Synthetic Lethal Interactions Between Non-Coding RNAs in Cancer Cells

Dual CRISPR-Interference Strategy for Targeting Synthetic Lethal Interactions Between Non-Coding RNAs in Cancer Cells

Published on : May 30, 2025

Nanoparticle Delivery of an Oligonucleotide Payload in a Glioblastoma Multiforme Animal Model

Nanoparticle Delivery of an Oligonucleotide Payload in a Glioblastoma Multiforme Animal Model

Published on : Sep 27, 2024

Selection-dependent and Independent Generation of CRISPR/Cas9-mediated Gene Knockouts in Mammalian Cells

Selection-dependent and Independent Generation of CRISPR/Cas9-mediated Gene Knockouts in Mammalian Cells

Published on : Jun 16, 2017

See more related videos