David House

13PUBLICATIONS
102CO-AUTHORS
Main group metal chemistryCheminformatics and quantitative structure-activity relationshipsMedical infection agents (incl. prions)Characterisation of biological macromoleculesBiomolecular modelling and design
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Publications (13)

|Jul 10, 2026
Proteome-Wide Target Identification Using Reactive Metallo-Scaffolds (r-mS): A Platform for Metallodrug Discovery.

|Nov 06, 2025
Covalent fragment screening to inhibit the E3 ligase activity of bacterial NEL enzymes SspH1 and SspH2.

Cassandra R Kennedy, Katherine A McPhie, Aini Vuorinen

|May 19, 2025
The fast-evolving FIKK kinase family of Plasmodium falciparum can be inhibited by a single compound.

Hugo Belda, David Bradley, Evangelos Christodoulou

|Jan 14, 2025
Enantioselective OTUD7B fragment discovery through chemoproteomics screening and high-throughput optimisation.

Aini Vuorinen, Cassandra R Kennedy, Katherine A McPhie

|Jan 02, 2025
Robust proteome profiling of cysteine-reactive fragments using label-free chemoproteomics.

George S Biggs, Emma E Cawood, Aini Vuorinen

|Dec 04, 2024
Expedited SARS-CoV-2 Main Protease Inhibitor Discovery through Modular 'Direct-to-Biology' Screening.

Harry Wilders, George Biggs, Sam M Rowe

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Frequent Collaborators

10 joint publications

Jacob T Bush

6 joint publications

Katrin Rittinger

4 joint publications

Jonathan Pettinger

4 joint publications

Mark Skehel