Yu Chen

12PUBLICATIONS
17CO-AUTHORS
Genome structure and regulationReaction engineering (excl. nuclear reactions)Cardiology (incl. cardiovascular diseases)Molecular targetsPredictive and prognostic markers
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Publications (12)

|Apr 09, 2026
Human cGAS Drives LINE-1 Transcriptional Activation to Trigger MAVS-Dependent Cellular Senescence.

Zhixi Chen, Lingjiang Chen, Xinyu Chen

|Oct 09, 2025
A cGAS-mediated mechanism in naked mole-rats potentiates DNA repair and delays aging.

Yu Chen, Zhixi Chen, Hao Wang

|Dec 12, 2023
Nuclear cGAS restricts L1 retrotransposition by promoting TRIM41-mediated ORF2p ubiquitination and degradation.

Zhengyi Zhen, Yu Chen, Haiyan Wang

|Nov 15, 2023
Impaired end joining induces cardiac atrophy in a Hutchinson-Gilford progeria mouse model.

Yu Chen, Shiqi Huang, Zhen Cui

|Nov 13, 2023
Androgen signaling stabilizes genomes to counteract senescence by promoting XRCC4 transcription.

Yu Chen, Zhengyi Zhen, Lingjiang Chen

|Apr 03, 2023
Loss of the receptors ER, PR and HER2 promotes USP15-dependent stabilization of PARP1 in triple-negative breast cancer.

Xiaoxiang Sun, Huanyin Tang, Yu Chen

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Frequent Collaborators

11 joint publications

Zhiyong Mao

3 joint publications

Ying Jiang

2 joint publications

Weina Zhang

2 joint publications

Shaorong Gao