Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

David A Sinclair

23PUBLICATIONS

115CO-AUTHORS

Life historiesCellular nervous systemMechanobiologyMedical biotechnology diagnostics (incl. biosensors)Food properties (incl. characteristics and health benefits)

Featured researcher

Get your video featured.

Publish with JoVE

Featured researcher

Get your video featured.

Publish with JoVE

Publications (23)

Sort by Publication Date:

|Nov 24, 2025

DNA Break-Induced Epigenetic Alterations Promote Plaque Formation and Behavioral Deficits in an Alzheimer's Disease Mouse Model.

Sydney Bartman, Dakota Hunter, Lauren Gaspar

|Sep 09, 2025

Emerging strategies, applications and challenges of targeting NAD<sup>+</sup> in the clinic.

Jianying Zhang, He-Ling Wang, Sofie Lautrup

|Sep 03, 2025

Single-Short Partial Reprogramming of the Endothelial Cells Decreases Blood Pressure via Attenuation of EndMT in Hypertensive Mice.

Laena Pernomian, Emily W Waigi, Vi Nguyen

|Mar 31, 2025

Invigorating discovery and clinical translation of aging biomarkers.

Erik Jacques, Chiara Herzog, Kejun Ying

|Dec 18, 2024

A bile acid could explain how calorie restriction slows ageing.

David A Sinclair

|Aug 21, 2024

Fertility protection during chemotherapy treatment by boosting the NAD(P)<sup>+</sup> metabolome.

Wing-Hong Jonathan Ho, Maria B Marinova, Dave R Listijono

Pageof 4

Frequent Collaborators

4 joint publications

Lindsay E Wu

3 joint publications

Mahdi Moqri

3 joint publications

Xiao Tian

3 joint publications

Vadim N Gladyshev

2 joint publications

Giuseppe Coppotelli

2 joint publications

Michael R MacArthur

2 joint publications

Elisa Warner

2 joint publications

Susan E Howlett

2 joint publications

Yuancheng Ryan Lu

2 joint publications

Steve Horvath

Frequent Collaborators

4 joint publications

Lindsay E Wu

3 joint publications

Mahdi Moqri

3 joint publications

Xiao Tian

3 joint publications

Vadim N Gladyshev

Top Related Videos

Detection of Neuritic Plaques in Alzheimer's Disease Mouse Model

Detection of Neuritic Plaques in Alzheimer's Disease Mouse Model

Published on : Jul 26, 2011

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies

Published on : Feb 06, 2019

Improved Renal Denervation Mitigated Hypertension Induced by Angiotensin II Infusion

Improved Renal Denervation Mitigated Hypertension Induced by Angiotensin II Infusion

Published on : May 26, 2022

See more related videos

Top Related Videos

Detection of Neuritic Plaques in Alzheimer's Disease Mouse Model

Detection of Neuritic Plaques in Alzheimer's Disease Mouse Model

Published on : Jul 26, 2011

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies

Published on : Feb 06, 2019

Improved Renal Denervation Mitigated Hypertension Induced by Angiotensin II Infusion

Improved Renal Denervation Mitigated Hypertension Induced by Angiotensin II Infusion

Published on : May 26, 2022

See more related videos