Kristen John

4PUBLICATIONS
16CO-AUTHORS
Cheminformatics and quantitative structure-activity relationshipsMolecular medicine
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Publications (4)

|May 11, 2026
Development of a Second-Generation RARα Selective Antagonist as an Orally Bioavailable, Effective, Safe, and Reversible Male Contraceptive.

|Apr 18, 2024
Incorporation of Three Extracyclic Arginine Residues into a Melanocortin Macrocyclic Agonist (c[Pro-His-DPhe-Arg-Trp-Dap-Lys(Arg-Arg-Arg-Ac)-DPro]) Decreases Food Intake When Administered Intrathecally or Subcutaneously Compared to a Macrocyclic Ligand Lacking Extracyclic Arginine Residues (c[Pro-His-DPhe-Arg-Trp-Dap-Ala-DPro)].

Mark D Ericson, Katie T Freeman, Courtney M Larson

|Jun 12, 2023
Discovery of a Pan-Melanocortin Receptor Antagonist [Ac-DPhe(pI)-Arg-Nal(2')-Orn-NH2] at the MC1R, MC3R, MC4R, and MC5R that Mediates an Increased Feeding Response in Mice and a 40-Fold Selective MC1R Antagonist [Ac-DPhe(pI)-DArg-Nal(2')-Arg-NH2].

Mark D Ericson, Linh T Tran, Sarah S Mathre

|Jan 26, 2023
Screening through Lead Optimization of High Affinity, Allosteric Cyclin-Dependent Kinase 2 (CDK2) Inhibitors as Male Contraceptives That Reduce Sperm Counts in Mice.

Erik B Faber, Nan Wang, Kristen John

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Frequent Collaborators

2 joint publications

Henry L Wong

2 joint publications

Carrie Haskell-Luevano

2 joint publications

Mark D Ericson

2 joint publications

Gunda I Georg