Dennis C Liotta

253PUBLICATIONS
205CO-AUTHORS
Biomolecular modelling and designCharacterisation of biological macromoleculesBiologically active moleculesCheminformatics and quantitative structure-activity relationshipsMolecular targets
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Publications (253)

|Sep 15, 2026
De Novo Design in an M1 Positive Allosteric Modulator Backup Program: The Discovery of VU6069863.

|Aug 20, 2026
Discovery of VU6052959/BI'7927: A Selective mGlu3 Positive Allosteric Modulator (PAM) from an Orthogonal Benzoxazine Chemotype.

|Jul 16, 2026
Discovery of VU6081679, a Novel Positive Allosteric Modulator of Metabotropic Glutamate Receptor 8 with Efficacy in a Preclinical Model of Parkinson's Disease.

|Jul 14, 2026
Optimization of Pyrazole-Based Activators of Kv3.1.

|Jul 07, 2026
Discovery of VU6077564: A Selective M1 Antagonist That Promotes Neurite Outgrowth in Adult Sensory Neurons.

|Jun 23, 2026
Discovery of VU6066098: A Selective and CNS-Penetrant mGlu2 NAM with Robust Antidepressant-, Antipsychotic-, and Procognitive-like Activity in Rodents.

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Frequent Collaborators

90 joint publications

Dennis Liotta

84 joint publications

Craig W Lindsley

76 joint publications

Carolyn Bertozzi

76 joint publications

Gunda I Georg