Gustavo Morrone Parfitt

5PUBLICATIONS
39CO-AUTHORS
Neurology and neuromuscular diseasesMedical molecular engineering of nucleic acids and proteinsAutonomic nervous systemEvolution of developmental systemsAdversarial machine learning
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Publications (5)

|Apr 17, 2026
ATP13A2 Loss of Function-Driven Polyamine Dysregulation Induces SAM Depletion and Epigenetic Astrocyte Toxicity.

|Dec 17, 2025
GPNMB is a biomarker for lysosomal dysfunction and is secreted via LRRK2-modulated lysosomal exocytosis.

Erin C Bogacki, Gustavo Morrone Parfitt, Adriana Cunha

|Jun 20, 2025
Mutations in PSEN1 predispose inflammation in an astrocyte model of familial Alzheimer's disease through disrupted regulated intramembrane proteolysis.

Oliver J Ziff, Gustavo Morrone Parfitt, Sarah Jolly

|Jan 10, 2024
Disruption of lysosomal proteolysis in astrocytes facilitates midbrain organoid proteostasis failure in an early-onset Parkinson's disease model.

Gustavo Morrone Parfitt, Elena Coccia, Camille Goldman

|Apr 14, 2022
Hippocampal-hypothalamic circuit controls context-dependent innate defensive responses.

Jee Yoon Bang, Julia Kathryn Sunstrum, Danielle Garand

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Frequent Collaborators

2 joint publications

Elena Coccia

2 joint publications

Joel Blanchard

1 joint publications

Jee Yoon Bang

1 joint publications

Melanie Woodin