Graham P Marsh

11PUBLICATIONS
44CO-AUTHORS
Medical molecular engineering of nucleic acids and proteinsProteins and peptidesData visualisation and computational (incl. parametric and generative) designMolecular targetsBiomolecular modelling and design
Featured researcher

Get your video featured.

JoVEPublish with JoVE
Journal

Publications (11)

|Oct 06, 2025
Discovery of a CNS active GSK3 degrader using orthogonally reactive linker screening.

Andreas Holmqvist, Nur Mehpare Kocaturk, Christina Duncan

|Apr 17, 2025
Structure-Guided Design of ISOX-DUAL-Based Degraders Targeting BRD4 and CBP/EP300: A Case of Degrader Collapse.

Anthony K Edmonds, Dimitrios-Ilias Balourdas, Graham P Marsh

|Mar 17, 2025
Development of p300-targeting degraders with enhanced selectivity and onset of degradation.

Graham P Marsh, Mark S Cooper, Sean Goggins

|Jan 16, 2025
Structure-Based Optimization of Pyridone α-Ketoamides as Inhibitors of the SARS-CoV-2 Main Protease.

Ravi Kumar Akula, Haifa El Kilani, Alina Metzen

|Jan 15, 2025
Evaluation of Cereblon-Directing Warheads for the Development of Orally Bioavailable PROTACs.

Marisa Actis, Joel Cresser-Brown, Elizabeth A Caine

Pageof 2