Gebhard Thoma
8PUBLICATIONS
20CO-AUTHORS
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Publications (8)
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|Feb 17, 2025
Discovery of GJG057, a Potent and Highly Selective Inhibitor of Leukotriene C4 Synthase.Gebhard Thoma, Wolfgang Miltz, Rudolf Waelchli
|Mar 13, 2024
Structure-Guided Elaboration of a Fragment-Like Hit into an Orally Efficacious Leukotriene A4 Hydrolase Inhibitor.Gebhard Thoma, Wolfgang Miltz, Honnappa Srinivas
|Feb 26, 2024
LTA4H inhibitor LYS006: Clinical PK/PD and safety in a randomized phase I clinical trial.Christian Loesche, Damien Picard, Benjamin Van Hoorick
|Nov 28, 2023
Discovery of Amino Alcohols as Highly Potent, Selective, and Orally Efficacious Inhibitors of Leukotriene A4 Hydrolase.Gebhard Thoma, Christian Markert, Rainer Lueoend
|Oct 31, 2023
Design of a Supersoft Topical JAK Inhibitor, Which Is Effective in Human Skin but Rapidly Deactivated in Blood.Gebhard Thoma, Odile Decoret, Eric Vangrevelinghe
|Jun 14, 2023
Novel Concept for Super-Soft Topical Drugs: Deactivation by an Enzyme-Induced Switch into an Inactive Conformation.Gebhard Thoma, Eric Vangrevelinghe, Alexandre Luneau
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Frequent Collaborators
2 joint publications
Till A Röhn
2 joint publications
Shin Numao
2 joint publications
Heike Otto
2 joint publications
Christian Loesche
2 joint publications
Christian Markert
2 joint publications
Carsten Spanka
1 joint publications
Damien Picard
1 joint publications
Imelda Schuhmann
1 joint publications
Petra Jäger
1 joint publications
Kai Klein
