Leslie S Kean

16PUBLICATIONS
159CO-AUTHORS
Innate immunityApplied immunology (incl. antibody engineering, xenotransplantation and t-cell therapies)Haematological tumoursImmunogenetics (incl. genetic immunology)Molecular targets
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Publications (16)

|Jul 03, 2026
Local and circulating cytotoxic CD4⁺ T cells are early markers of disease activity in pediatric Crohn's disease.

|Jul 03, 2026
Human CD8-iTreg are potent GVHD suppressors and tumoricidal effectors by release of Granzyme-K + Supramolecular Attack Particles.

|Feb 27, 2026
Differential effects of two common GVHD prophylaxis regimens on the gut microbiome: Results from the BMT CTN 1801 study.

Jakob Wirbel, Wael Saber, Michael J Martens

|Nov 24, 2025
Divergent T Cell Phenotypes Define Pediatric Crohn's Disease and Ulcerative Colitis.

Leonard Nettey, Hengqi Betty Zheng, Joseph C Devlin

|Sep 26, 2025
PTPN2-KO CAR-T Cells Demonstrate Enhanced Effector Function, CNS Infiltration, and Toxicity in a Non-Human Primate CAR-T Model.

Francesca Alvarez Calderon, Ryan A Fleming, Marlana Winschel

|Feb 03, 2025
Deficiency of T follicular helper cell Tet3 DNA demethylation inhibits pathogenic IgG2c class switching and chronic GVHD.

Michael C Zaiken, Sujeong Jin, Cameron S McDonald-Hyman

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Frequent Collaborators

7 joint publications

Victor Tkachev

7 joint publications

Bruce R Blazar

5 joint publications

Hengqi Zheng

5 joint publications

Ulrike Gerdemann