Jacob S Roth

9PUBLICATIONS
62CO-AUTHORS
Cheminformatics and quantitative structure-activity relationshipsEpigenetics (incl. genome methylation and epigenomics)Molecular targetsMedical infection agents (incl. prions)Pyrometallurgy
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Publications (9)

|Sep 16, 2025
SAR Studies around the SULT1A1-Activated Alkylator YC-1 as Cytotoxic Agents against Biliary Tract Cancer Cells.

Ke Kong, Wei Zhao, Jonathan H Shrimp

|Jul 17, 2025
PRMT5 activity sustains histone production to maintain genome integrity.

Jacob S Roth, Joseph D DeAngelo, Dejauwne L Young

|Jun 12, 2025
Identification of antibody-drug conjugate payloads which are substrates of ATP-binding cassette drug efflux transporters.

Jacob S Roth, Hui Guo, Lu Chen

|Aug 16, 2024
Productive mRNA Chromatin Escape is Promoted by PRMT5 Methylation of SNRPB.

Joseph D DeAngelo, Maxim I Maron, Jacob S Roth

|Jul 13, 2024
Preclinical Therapeutic Efficacy of RAF/MEK/ERK and IGF1R/AKT/mTOR Inhibition in Neuroblastoma.

Stacey Stauffer, Jacob S Roth, Edjay R Hernandez

|Nov 16, 2023
Birinapant selectively enhances immunotoxin-mediated killing of cancer cells conditional on the IAP protein levels within target cells.

Antonella Antignani, Maria Teresa Bilotta, Jacob S Roth

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Frequent Collaborators

6 joint publications

Matthew D Hall

3 joint publications

David Shechter

3 joint publications

Maxim I Maron

3 joint publications

Simone Sidoli