Ruxandra Dafinca
6PUBLICATIONS
46CO-AUTHORS
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Publications (6)
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|Apr 10, 2025
High-throughput screen of 100 000 small molecules in C9ORF72 ALS neurons identifies spliceosome modulators that mobilize G4C2 repeat RNA into nuclear export and repeat associated non-canonical translation.Maartje J Luteijn, Varun Bhaskar, Dominic Trojer
|Oct 23, 2024
Dynactin-1 mediates rescue of impaired axonal transport due to reduced mitochondrial bioenergetics in amyotrophic lateral sclerosis motor neurons.Ruxandra Dafinca, Carlota Tosat-Bitrian, Emily Carroll
|Dec 18, 2023
Mutant GGGGCC RNA prevents YY1 from binding to Fuzzy promoter which stimulates Wnt/β-catenin pathway in C9ALS/FTD.Zhefan Stephen Chen, Mingxi Ou, Stephanie Taylor
|Sep 22, 2023
C9orf72-ALS human iPSC microglia are pro-inflammatory and toxic to co-cultured motor neurons via MMP9.Björn F Vahsen, Sumedha Nalluru, Georgia R Morgan
|Sep 14, 2022
Poly(ADP-ribose) promotes toxicity of C9ORF72 arginine-rich dipeptide repeat proteins.Junli Gao, Quinlan T Mewborne, Amandeep Girdhar
|Nov 26, 2021
Axonal TDP-43 condensates drive neuromuscular junction disruption through inhibition of local synthesis of nuclear encoded mitochondrial proteins.Topaz Altman, Ariel Ionescu, Amjad Ibraheem
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Frequent Collaborators
6 joint publications
Kevin Talbot
3 joint publications
Björn F Vahsen
2 joint publications
Jakub Scaber
1 joint publications
Dominik Priesmann
1 joint publications
Florence Rage
1 joint publications
Amir Dori
1 joint publications
Marcus Krüger
1 joint publications
Eran Perlson
1 joint publications
Nicole C Meisner-Kober
1 joint publications
Quinlan T Mewborne
