Xin Han

9PUBLICATIONS
9CO-AUTHORS
Cheminformatics and quantitative structure-activity relationshipsMolecular targetsCancer therapy (excl. chemotherapy and radiation therapy)Organometallic chemistryPharmacogenomics
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Publications (9)

|Aug 06, 2026
Discovery of spirocyclic amide scaffolds as novel neddylation E1 inhibitors to suppress the growth and survival of lung cancer cells.

|May 29, 2026
Discovery of a Novel Potent and Orally Efficacious PGK1 Inhibitor C67-47 for the Treatment of Human Pancreatic Cancer.

|Apr 13, 2026
Discovery of a First-in-Class Murine Double Minute 2-Recruiting Positive Transcription Elongation Factor B PROTAC Degrader With Selective Antitumor Activity.

Xian Guan, Long Xie, Hanjun Guo

|Nov 11, 2025
Kill Two Birds with One Stone: An Efficient and Potent AR CBS-Targeted Degrader Reverses Breast Cancer Resistance via Concurrent AR Degradation and ERα Transcriptional Suppression.

Yihe Wu, Baohua Xie, Jinsen Liang

|Oct 07, 2025
Copper-Catalyzed Asymmetric C-H Sulfilimination of Arenes via HAT-Primed C-S Radical-Radical Coupling.

Yishou Wang, Yucai Mu, Xin Han

|Oct 06, 2025
Discovery of LD-110 as an Effective LSD1 PROTAC Degrader for the Treatment of Esophagus Squamous Cancer.

Jiezhen Zhuo, Danyi Zhai, Lihua Liu

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Frequent Collaborators

3 joint publications

Duxin Sun

3 joint publications

Shaomeng Wang

1 joint publications

Chong Qin

1 joint publications

Tianfeng Xu