Gilbert Di Paolo

11PUBLICATIONS

159CO-AUTHORS

Medical infection agents (incl. prions)Medical virologyMolecular targetsNeurology and neuromuscular diseasesNeurogenetics

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Publications (11)

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|Jul 08, 2026

Microglial TDP-43 mediates myelin refinement and represses Tyrobp cryptic exon inclusion in mice.

|Jan 24, 2026

TREM2 expression level is critical for microglial state, metabolic capacity and efficacy of TREM2 agonism.

Astrid F Feiten, Kilian Dahm, Kai Schlepckow

|Dec 03, 2025

Loss of PILRA promotes microglial immunometabolism to reduce amyloid pathology in cell and mouse models of Alzheimer's disease.

Tanya N Weerakkody, Hanna Sabelström, Shan V Andrews

|Aug 18, 2025

Investigational eIF2B activator DNL343 modulates the integrated stress response in preclinical models of TDP-43 pathology and individuals with ALS in a randomized clinical trial.

Brittany N Flores, Seungyoon B Yu, Isaac V Cohen

|Dec 04, 2024

Myeloid cell-specific loss of NPC1 in mice recapitulates microgliosis and neurodegeneration in patients with Niemann-Pick type C disease.

Lina Dinkel, Selina Hummel, Valerio Zenatti

|Jun 05, 2024

Peripheral expression of brain-penetrant progranulin rescues pathologies in mouse models of frontotemporal lobar degeneration.

Marvin Reich, Matthew J Simon, Beate Polke

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Frequent Collaborators

Joseph W Lewcock

Christian Haass

Thomas Sandmann

Kathryn M Monroe

Jung H Suh

Arthur Liesz

Dominik Paquet

Anja Capell

Matthias Brendel

Sonnet S Davis

Frequent Collaborators

Joseph W Lewcock

Christian Haass

Thomas Sandmann

Kathryn M Monroe