Christine Helsen

10PUBLICATIONS
59CO-AUTHORS
Reaction engineering (excl. nuclear reactions)Developmental genetics (incl. sex determination)Characterisation of biological macromoleculesHaematological tumoursPredictive and prognostic markers
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Publications (10)

|Mar 21, 2024
Rational evolution for altering the ligand preference of estrogen receptor alpha.

Roy Eerlings, Purvi Gupta, Xiao Yin Lee

|Feb 22, 2023
Study of novel androgen receptor V770 variant in androgen insensitivity syndrome patients reveals the transitional state of the androgen receptor ligand binding domain homodimer.

Christine Helsen, Maria Santa Rocca, Tien T Nguyen

|Oct 11, 2022
Exploiting Ligand-binding Domain Dimerization for Development of Novel Androgen Receptor Inhibitors.

Christine Helsen, Tien T Nguyen, Xiao Yin Lee

|Feb 15, 2022
The T850D Phosphomimetic Mutation in the Androgen Receptor Ligand Binding Domain Enhances Recruitment at Activation Function 2.

Christine Helsen, Tien Nguyen, Thomas Vercruysse

|Jan 27, 2022
Antizyme Inhibitor 1 Regulates Matrikine Expression and Enhances the Metastatic Potential of Aggressive Primary Prostate Cancer.

Thomas Van den Broeck, Lisa Moris, Thomas Gevaert

|Oct 18, 2021
The androgen receptor depends on ligand-binding domain dimerization for transcriptional activation.

Sarah El Kharraz, Vanessa Dubois, Martin E van Royen

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