Melike Çağlayan

10PUBLICATIONS
2CO-AUTHORS
Lasers and quantum electronicsCell and nuclear divisionSignal transductionCell metabolismCell development, proliferation and death
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Publications (10)

|Dec 10, 2025
Processing of DNA single-strand breaks with oxidatively damaged ends by LIG1.

Kanal E Balu, Danah Almohdar, Camden Lerner

|Dec 05, 2025
Impaired nick recognition and ligation efficiency by LIG1 K845N variant linked to Huntington's disease.

Jacob Ratcliffe, Camden E Lerner, Kanal Balu

|Jul 16, 2025
Single-molecule analysis of gap and nick binding by LIG1 and LIG3α at the final step of DNA repair.

Surajit Chatterjee, Kar Men Lee, Kanal Balu

|Nov 22, 2024
Biochemical, structural, and single-molecule characterization of LIG1 active site mutants demonstrate role of F635 and F872 residues for faithful ligation.

Mustafa Kalaycioğlu, Mitchell Gulkis, Kar Men Lee

|Oct 15, 2024
Probing the mechanism of nick searching by LIG1 at the single-molecule level.

Surajit Chatterjee, Loïc Chaubet, Aafke van den Berg

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