Matthew D Cheeseman

8PUBLICATIONS
51CO-AUTHORS
Molecular targetsNonlinear optics and spectroscopyProteins and peptidesBiomolecular modelling and designCheminformatics and quantitative structure-activity relationships
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Publications (8)

|Jan 09, 2025
NXP800 Activates the Unfolded Protein Response, Altering AR and E2F Function to Impact Castration-Resistant Prostate Cancer Growth.

Jonathan Welti, Denisa Bogdan, Ines Figueiredo

|Jul 19, 2023
Determination of Ligand-Binding Affinity (Kd) Using Transverse Relaxation Rate (R2) in the Ligand-Observed 1H NMR Experiment and Applications to Fragment-Based Drug Discovery.

Manjuan Liu, Amin Mirza, P Craig McAndrew

|Apr 05, 2023
HSF1 Pathway Inhibitor Clinical Candidate (CCT361814/NXP800) Developed from a Phenotypic Screen as a Potential Treatment for Refractory Ovarian Cancer and Other Malignancies.

A Elisa Pasqua, Swee Y Sharp, Nicola E A Chessum

|Nov 15, 2019
Kinetic Optimization of Lysine-Targeting Covalent Inhibitors of HSP72.

Jonathan Pettinger, Michael Carter, Keith Jones

|Dec 15, 2017
Demonstrating In-Cell Target Engagement Using a Pirin Protein Degradation Probe (CCT367766).

Nicola E A Chessum, Swee Y Sharp, John J Caldwell

|Aug 31, 2017
Lysine-Targeting Covalent Inhibitors.

Jonathan Pettinger, Keith Jones, Matthew D Cheeseman

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Frequent Collaborators

7 joint publications

Keith Jones

4 joint publications

Nicola E A Chessum

3 joint publications

Paul Clarke

3 joint publications

Paul Workman