Sebastian Frechen

5PUBLICATIONS
14CO-AUTHORS
PharmacogenomicsPredictive and prognostic markersPharmaceutical delivery technologies
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Publications (5)

|Oct 03, 2024
PBPK modeling: What is the role of CYP3A4 expression in the gastrointestinal tract to accurately predict first-pass metabolism?

Justine Henriot, André Dallmann, François Dupuis

|Dec 18, 2023
Assessment of the CYP3A4 Induction Potential by Carbamazepine: Insights from Two Clinical DDI Studies and PBPK Modeling.

Friederike Kanefendt, André Dallmann, Huijun Chen

|Oct 05, 2023
Applied physiologically-based pharmacokinetic modeling to assess uridine diphosphate-glucuronosyltransferase-mediated drug-drug interactions for Vericiguat.

Sebastian Frechen, Ibrahim Ince, André Dallmann

|Nov 16, 2021
Physiologically-based pharmacokinetic modeling to predict CYP3A4-mediated drug-drug interactions of finerenone.

Thomas Wendl, Sebastian Frechen, Michael Gerisch

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