Warren Thompson

14PUBLICATIONS
64CO-AUTHORS
Cheminformatics and quantitative structure-activity relationshipsProteins and peptidesHumanitarian disasters, conflict and peacebuildingMetal organic frameworksChemical and thermal processes in energy and combustion
Featured researcher

Get your video featured.

JoVEPublish with JoVE
Journal

Publications (14)

|Oct 13, 2026
Syndirella: synthesis-directed fragment elaboration enables extensive and cost-effective binding site exploration beyond catalog compounds.

|Sep 16, 2026
A resource-efficient structure-based workflow for fragment progression enables parallel hit discovery and validation of functionally diverse modulators of NCS-1 protein-protein interactions.

|Jan 15, 2026
Structure-activity relationships can be directly extracted from high-throughput crystallographic evaluation of fragment elaborations in crude reaction mixtures.

Harold Grosjean, Kate K Fieseler, Rubén Sanchez-Garcia

|Oct 08, 2025
Combined crystallographic fragment screening and deep mutational scanning enable discovery of Zika virus NS2B-NS3 protease inhibitors.

Xiaomin Ni, R Blake Richardson, Andre Schutzer Godoy

|Feb 24, 2025
Crystallographic fragment screening and deep mutational scanning of Zika virus NS2B-NS3 protease enable development of resistance-resilient inhibitors.

Frank von Delft, Xiaomin Ni, R Richardson

|Feb 11, 2025
Binding-Site Purification of Actives (B-SPA) Enables Efficient Large-Scale Progression of Fragment Hits by Combining Multi-Step Array Synthesis With HT Crystallography.

Harold Grosjean, Anthony Aimon, Storm Hassell-Hart

Pageof 3

Frequent Collaborators

11 joint publications

Frank von Delft

7 joint publications

Lizbé Koekemoer

7 joint publications

Charlie W E Tomlinson

6 joint publications

Peter Marples