Marika de Hoop-Sommen

7PUBLICATIONS
13CO-AUTHORS
Toxicology (incl. clinical toxicology)Environmental epidemiologyPharmacogenomics
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Publications (7)

|Sep 08, 2026
Supporting clinical guidelines for opioid conversion to methadone and tapering to prevent withdrawal in critically ill children using physiology based pharmacokinetic modeling and simulation.

|Jan 29, 2026
Do the redefined EUCAST susceptibility categories warrant adjustment of paediatric antibiotic dosages? Pragmatic physiologically based pharmacokinetic modelling of four commonly used agents.

Marika A de Hoop-Sommen, Jolien J M Freriksen, Joyce E M van der Heijden

|Jul 02, 2025
Physiologically Based Pharmacokinetic Modeling-Based Evaluation of Current Carbamazepine and Valproic Acid Dosing Guidelines for Pediatric Epilepsy Treatment.

Joyce E M van der Heijden, Violette Gijsen, Anne M van Uden

|Aug 09, 2023
Physiologically-Based Pharmacokinetic Modeling for Drug Dosing in Pediatric Patients: A Tutorial for a Pragmatic Approach in Clinical Care.

Joyce E M van der Heijden, Jolien J M Freriksen, Marika A de Hoop-Sommen

|Nov 12, 2022
Feasibility of a Pragmatic PBPK Modeling Approach: Towards Model-Informed Dosing in Pediatric Clinical Care.

Joyce E M van der Heijden, Jolien J M Freriksen, Marika A de Hoop-Sommen

|Oct 06, 2022
Physiologically Based Pharmacokinetic (PBPK) Model-Informed Dosing Guidelines for Pediatric Clinical Care: A Pragmatic Approach for a Special Population.

Jolien J M Freriksen, Joyce E M van der Heijden, Marika A de Hoop-Sommen

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Frequent Collaborators

6 joint publications

Saskia N de Wildt

5 joint publications

Jolien J M Freriksen

5 joint publications

Joyce E M van der Heijden

4 joint publications

Rick Greupink