John R Butler

3PUBLICATIONS
55CO-AUTHORS
Cheminformatics and quantitative structure-activity relationshipsMolecular targets
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Publications (3)

|Aug 13, 2026
Discovery and Optimization of a WRN Helicase Inhibitor Series through Structure-Guided Drug Design from a Covalent Fragment Binding Insight.

|Aug 13, 2026
Property-Biased Covalent DNA-Encoded Library Screening Enabled the Discovery of AM-8719, A Structurally Novel, CNS-Penetrant KRAS G12C Inhibitor.

|Sep 16, 2024
AMG 193, a Clinical Stage MTA-Cooperative PRMT5 Inhibitor, Drives Antitumor Activity Preclinically and in Patients with MTAP-Deleted Cancers.

Brian Belmontes, Katherine K Slemmons, Chun Su

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Frequent Collaborators

2 joint publications

Nuria Tamayo

1 joint publications

Brian Belmontes

1 joint publications

Katherine K Slemmons

1 joint publications

Chun Su